View our injection videoSomatuline Depot is injected in an easy, two-step injection process. Learn more about how easy it is to inject Somatuline Depot.
While your healthcare professional may adjust your dosage periodically, treating a condition like acromegaly is something you may continue for the rest of your life.
The good news is that, with medication and surgery or radiation, acromegaly can be controlled long-term. Also with treatment, people with acromegaly may live longer than those who go untreated.
Like all other medications, Somatuline Depot can cause side effects. Learn about possible side effects of Somatuline Depot.
If you take Somatuline Depot for acromegaly, you are not alone. Learn about resources available to you.
Learn about insurance coverage, pharmacies that carry Somatuline Depot, and the Reimbursement Hotline.
Somatuline® Depot (lanreotide) Injection is a somatostatin analog indicated for the long-term treatment of patients with acromegaly who have had an inadequate response to or cannot be treated with surgery and/or radiotherapy.
Lanreotide may reduce gallbladder motility and lead to gallstone formation. Periodic monitoring may be needed. Patients treated with Somatuline® Depot may experience hypoglycemia or hyperglycemia. Glucose levels monitoring is recommended and antidiabetic treatment adjusted accordingly. Lanreotide may lead to a decrease in heart rate. Use with caution in at-risk patients.
Patients with moderate and severe renal impairment or moderate and severe hepatic impairment should begin treatment with Somatuline® Depot 60mg.
There are no adequate and well controlled studies in pregnant women. Because animal reproduction studies are no always predictive of human responses, Somatuline® Depot should be used during pregnancy only if the potential benefit justifies risk to the fetus. A decision should be made whether to discontinue nursing or discontinue the drug taking into account the importance of the drug to the mother.
Somatuline® Depot may decrease the bioavailability of cyclosporine. Cyclosporine dose may need to be adjusted to maintain levels.
Patients receiving beta-blockers, calcium channel blockers, or other drugs that affect heart rate may need dose adjustments. Somatuline® Depot may reduce the intestinal absorption of co-administered drugs. Caution should be used.
The most common adverse reactions (incidence >5%) are diarrhea, cholelithiasis, abdominal pain, nausea, injection site reaction, flatulence, arthralgia, and loose stools.
Please see Full Prescribing
Information for additional important information.
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