Watch this brief video showing how Somatuline^® Depot (lanreotide) Injection should be injected, or read the illustrated text version below, if you prefer.

Hello. I'm Daphne Adelman, a nurse at Northwestern University, The Feinberg School of Medicine in Chicago.

Somatuline^® Depot provides powerful long-term reductions in IGF-1 and GH levels. Therapeutic drug levels are achieved within 24 hours of the first dose. And you can feel confident your patient will receive a complete dose with each injection, with its ready-to-use, prefilled syringe. With Somatuline^® Depot, you and your patients can enjoy convenience and freedom like never before.

Today, I will explain and demonstrate how Somatuline^® Depot (lanreotide) Injection provides nurses, patients, and caregivers freedom with its ready-to-go delivery system.

Somatuline^® Depot (lanreotide) Injection is designed for convenience.

It is the only four-week acromegaly therapy available in a prefilled syringe-and the only long-acting somatostatin analog that does not require reconstitution.

Since Somatuline^® Depot (lanreotide) Injection comes in a ready-to-use syringe, all of the complex steps of reconstitution have been done for you.

A prefilled syringe allows delivery of a complete dose every time.

Somatuline^® Depot (lanreotide) Injection is also designed to be patient friendly. It's the only 28-day acromegaly therapy that is given by a deep subcutaneous injection instead of an intramuscular injection.

The Somatuline^® Depot prefilled syringe delivers a low-volume injection, just .2 to .5 milliliters of medication. Less than 10% of patients reported local side effects, which were more common at the start of treatment and less common as treatment continued.

And there was only a 1.9% treatment-related discontinuation rate after 52 weeks.

In fact, giving an injection of Somatuline^® Depot is a simple, easy three-step process.

Once you've removed Somatuline^® Depot (lanreotide) Injection from the refrigerator, allowing it to come to room temperature for 30 minutes, and after you've checked the packaging and expiration data on the carton or laminated pack, wash your hands with antibacterial soap and clean the injection site with rubbing alcohol.

Remove the transparent plunger protector, then the rubber needle cap with a twisting motion.

We're now ready to inject Somatuline^® Depot (lanreotide) Injection into the upper external part of the buttock, alternating between the left and right buttock each month.

Patients may sit or stand for their injection. Thin patients may want to sit on their side. When injecting thin patients, do not worry if you feel that the needle has gone intramuscularly. The effect of the drug will be the same.

Now we're ready for Step 1: Spread the skin around the injection site flat. Do not pinch the skin. With your dominant hand, hold the needle as you would a dart. You don't need to aspirate the needle. The bevel should face downward, towards the patient's feet. Insert the needle rapidly at a 90-degree angle to the skin.

Now for Step 2: Using your dominant hand, apply constant and steady pressure to the plunger. Continue to apply pressure without moving the needle. The solution is thick, so it may take up to 20 seconds to deliver all the medication. Make sure you push the plunger all the way down, past the flange, so the patient receives a full dose of medication.

Step 3 is to remove the needle. Withdraw the needle steadily and apply pressure for about 5 seconds. Do not rub or massage. You may wish to apply a bandage. Comply with your institution's policy for the proper and safe disposal of the syringe.

Once a patient receives an injection, therapeutic levels of Somatuline^® Depot (lanreotide) Injection are achieved within only 24 hours, providing powerful, long-term reductions in IGF-1 and GH levels.

Somatuline^® Depot (lanreotide) Injection is also long-lasting, requiring only one injection every 28 days.

So that's all there is to it. The advanced injection process for Somatuline^® Depot is as easy as 1-2-3. It's easy for you, and it's easier on your patients.

*Please note that this coverage is not available for patients on Medicare, Medicaid, and residents of Massachusetts.