Watch this brief video showing how Somatuline Depot should be injected, or read the illustrated text version below, if you prefer.

Injection Video: QuickTime or Windows

Hello. I'm Daphne Adelman, a nurse at Northwestern University, The Feinberg School of Medicine in Chicago.

Today, I will explain and demonstrate how Somatuline Depot provides nurses, patients, and caregivers freedom with its ready-to-go delivery system.

Somatuline Depot is designed for convenience.

It is the only four-week acromegaly therapy available in a prefilled syringe-and the only long-acting somatostatin analog that does not require reconstitution.

Since Somatuline Depot comes in a ready-to-use syringe, all of the complex steps of reconstitution have been done for you.

This eliminates the most common difficulties nurses and some patients experience with some injections, including needle clogging or blockage.

Somatuline Depot is also designed to be patient friendly. It's the only four-week acromegaly therapy that is given by a deep subcutaneous injection instead of an intramuscular injection.

Somatuline Depot prefilled syringes have shorter needles than those used to inject Sandostatin LAR.

Also, the injection volume of Somatuline^® Depot is almost 80% less volume than that of Sandostatin^® LAR Depot.

With the short needle, small injection volume, and the fact that Somatuline Depot is a subcutaneous injection instead of an intramuscular injection, it is not surprising that less than 10% of patients reported local side effects, which were more common at the start of treatment and less common as treatment continued.

And there was only a 1.9% treatment-related discontinuation rate after 52 weeks.

In fact, giving an injection of Somatuline Depot is a simple, easy two-step process.

Once you've removed Somatuline Depot from the refrigerator, allowing it to come to room temperature for 30 minutes, and after you've checked the packaging and expiration data on the carton or laminated pack, wash your hands with antibacterial soap and clean the injection site with rubbing alcohol.

Remove the transparent plunger protector, then the rubber needle cap with a twisting motion.

We're now ready to inject Somatuline Depot into the upper external part of the buttock-alternating between the left and right buttock each month.

With Somatuline Depot, there's no need to fold or press on the skin at the injection site. Just hold the skin around the injection site flat and insert the needle rapidly to its full length, keeping it perpendicular to the skin.

Apply constant pressure on the plunger until all of the medication is injected. Don't rub or massage the injection site. That's all there is to it. You're done.

Once a patient receives an injection, therapeutic levels of Somatuline Depot are achieved within only 24 hours, providing powerful, long-term reductions in IGF-1 and GH levels.

Somatuline Depot is also long-lasting, requiring only one injection every four weeks.

That's all there is to giving an injection of Somatuline Depot. As you can see, it's a simple and easy process for you. And it's easier on your patients.